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May 10th, 2013. A new method, PRIME, an abbreviation for PRoperty Informed Model of Evolution, which is capable of asking the question: which biochemical properties are driving substitutions at a given site, e.g. if a site is positively selected, then which properties are being selected for / against. This analysis is also a demostration of the redesigned datamonkey interface, extensively using standard libraries and tools, for formatting and visualization in the browser.
February 19rd, 2013. The FUBAR method paper has now been published in Mol Biol and Evol. Give this much faster (can process 1000 sequences < 10 mins) and statistically more robust method than REL (or PAML) a try, or see the papers which already cited it.
Welcome to the free public server for comparative analysis of sequence alignments using state-of-the-art statistical models. This service is brought to you by the viral evolution group at the School Of Medicine of the University of California, San Diego. Over its lifetime has processed 317952 analyses at a rate of 276.333 jobs/day (over the last 30 days). can help you answer the following questions ( publications citing

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