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May 10th, 2013. A new method, PRIME, an abbreviation for PRoperty Informed Model of Evolution, which is capable of asking the question: which biochemical properties are driving substitutions at a given site, e.g. if a site is positively selected, then which properties are being selected for / against. This analysis is also a demostration of the redesigned datamonkey interface, extensively using standard libraries and tools, for formatting and visualization in the browser.
February 19rd, 2013. The FUBAR method paper has now been published in Mol Biol and Evol. Give this much faster (can process 1000 sequences < 10 mins) and statistically more robust method than REL (or PAML) a try, or see the papers which already cited it.
Welcome to the free public server for comparative analysis of sequence alignments using state-of-the-art statistical models. This service is brought to you by the viral evolution group at the School Of Medicine of the University of California, San Diego. Over its lifetime Datamonkey.org has processed 252006 analyses at a rate of 207.333 jobs/day (over the last 30 days).

Datamonkey.org can help you answer the following questions ( publications citing datamonkey.org):

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Datamonkey.org is implemented on the Applecross/San Diego Alliance cluster which was funded jointly by the UCSD CFAR grant, NSF award 0714991 and a Medical Research Council (UK) grant to the University of Edinburgh (to Prof. Andy Leigh Brown). Further support provided by the UCSD Center for AIDS Research BIT Core. Our data privacy policy   Copyright notice
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